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Using human dental pulp stem cells and periodontal ligament cells, scaffold and growth factors, we are aiming to regenerate human tooth. For this, first we are charactering the dentine, cementum and enamel of the human tooth by analyzing their matrix proteins and investigating growth factors to stimulate those cells. |
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We are going to utilize the optimal scaffold for this purpose including ceramics and non-ceramic biomaterials. |
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Studies on the cellular differentiation of bone marrow and dental pulp stem cells, and regulation and delivery of genes for development of Bio-tooth. |
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The purpose of this study was to establish fundamental technologies for regeneration of bio-tooth. To achieve this purpose. We focused on development of technologies related to potentiation of function of dental and non-dental mesenchymal stem cells, and to production of materials derived from human tooth. |
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Therefore, we mainly studied on |
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characterization of differentiation characteristics of bone marrow mesenchymal stem cells (BMSCs) and dental pulp stem cells (DPSCs), |
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genome-wide screening and validation of genes that fluctuated during differentiation of BMSCs and DPSCs, |
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characterization of constituents extracted from tooth, |
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preparation of scaffold derived from tooth, |
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development of techniques for implantation of cell-scaffold composites for in vivo tooth regeneration. |
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Our results can be used for the regeneration of biotooth. |
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Home > Research > Biotooth regeneration
